[HTML][HTML] Spacers and valved holding chambers—the risk of switching to different chambers

F Lavorini, C Barreto, JFM van Boven, W Carroll… - The Journal of Allergy …, 2020 - Elsevier
between inhaler activation and inhalation led to a greater likelihood of uncontrolled asthma
symptoms and a higher rate of … of bronchodilators delivered by virtually any inhalation device

[PDF][PDF] The Global Inhaler Effectiveness Score (GIES): A Novel Tool for Assessing and Ranking in vitro Properties and Patients Usability of Dry Powder Inhalers …

F Buttini, F Lavorini, R Bettini, SE Pedersen… - JOURNAL OF …, 2018 - aerosol-soc.com
Inhaled drug delivery is the cornerstone treatment for asthma … model to compare direct-acting
bronchodilators.[8-9]). As … principle of functional antagonism between muscarinic and β- …

[PDF][PDF] Assessment of Asthmatic Patients Treated with Salbutamol: A Hospital Based Study

F Siddique, GV Diwakar - Journal of Advanced Medical and Dental …, 2018 - jamdsr.com
Speed of onset of bronchodilator response to salbutamol inhaled via different devices in
asthmatics: a bioassay based on functional antagonism. Br J Clin Pharmacol. 2006 Oct;62(4):…

Considerations in establishing bioequivalence of inhaled compounds

I Mayers, M Bhutani - Expert Opinion on Drug Delivery, 2018 - Taylor & Francis
… dose–response relationships for inhaled asthma and COPD drugs should be considered.
Clinical response to a bronchodilatorInhaler devices have been designed based on patient …

Determining the optimal time to assess the reversibility of airway obstruction

J El Ghoul, M Abouda, M Triki, A Ghourabi, R Charfi - Lung India, 2019 - journals.lww.com
function is reached after inhalation of salbutamol and to define the optimal time of bronchodilator
response … patients had asthma and were classified with moderate persistent asthma (46…

Use of spacers for patients treated with pressurized metered dose inhalers: focus on the VENTOLIN™ Mini Spacer

G Anderson, N Johnson, A Mulgirigama… - Expert Opinion on …, 2018 - Taylor & Francis
… for salbutamol delivery in patients with asthma in two studies, … been seen for other inhaled
drugs for asthma and chronic … nebulizers at inducing bronchodilation with salbutamol [Citation…

Inhalation and nasal formulations

J Mitchell - Developing Drug Products in an Aging Society: From …, 2016 - Springer
… of the inhaler with the ideal onset of inhalation, should be … indicated for the treatment of asthma
and COPD. The former … have quite different function to either of the bronchodilator inhaled

Management with Inhaled ß2-Agonists

TJ Gaeta - api.taylorfrancis.com
… β-agonists are functional antagonists of bronchoconstricting … between life-threatening asthma
and either oral or inhaled β-… -dose inhaler and nebulizer solution: bioassay by histamine …

Therapeutic potential of controlled delivery systems in asthma: preclinical development of flavonoid-based treatments

SM Borghi, TH Zaninelli, JB Carra, OK Heintz… - Pharmaceutics, 2022 - mdpi.com
… to the most varied stimuli such as exercise and inhaled … corticosteroids promotes
bronchodilation in acute asthma. Systemic … There are receptor antagonists and synthesis inhibitors …

The importance of inhaler adherence in severe asthma and its relationship to clinical outcomes

M Mokoka - 2020 - repository.rcsi.com
… For example, Sch 527123, a CXCR 1/2 receptor antagonist … additional diagnostic tests such
as preand post-bronchodilator … how adherence to maintenance inhaled asthma therapy was …